Biotech Process Automation
Innovative Workflow Optimization Solutions
About BPA
Alfred Haddad
Specializing in the Design, Development and Implementation of Automation Solutions, such as Robotic Work-Cells, Custom Instruments and Workflow Optimization for Life-Science.
30 years of Laboratory Automation, Assay Development and Workflow Optimization for Regulated Biotech Diagnostic Testing Companies, Combined with a Career in Systems Engineering and Project Management.
Services
Extensive Automation and Process Development experience in Genomics (Oncology, Liquid Biopsy, Whole Genome, Whole Exome, Transtricptome)
Meta-Genomics, Proteomics, Viral and Microbial Infectious Diseases.
Work with Knowledgeable Experts and Feel Confident in the Designed Solution.
With Our Deep Experience in Automation, Assay Development and Workflow Optimization, We Study Your Product and Processes, Then Design, Develop and Deliver a Custom Solution that Meets your Current and Future Needs
- Automation Solutions Development for Medium to High-Throughput Environments
- Custom Instruments and Systems Tailored to your Processes and Needs
- Enhance the Workflows and the Bio-Chemistry to Optimize the Performance
- Reduce Safety and Ergonomic Risks with Engineered Solutions and Tools
- Integrate LIMS and Data Management Tools to Ensure Samples Integrity
- Streamline Reagents Supply into the Process to Enhance Throughput
- Reduce COGS, Streamline Operations, Reduce Risks and Eliminate Errors
- Design for CAP/CLIA, cGMP and IVD Regulatory Requirements
Automation Systems
Robotic Work-Cells
Integrated Systems
Liquid Handling
Custom Instruments
Custom Lab-ware
Ergonomic Solutions
Data Management
Samples Storage
Micro-Fluidic Systems
Workflow Optimization
Workflow Enhancements
Assay Optimization
Samples Tracking
Ergonomic Risks Mitigation
Lean Manufacturing
Constraints Management
Design for Six Sigma
Failure Modes Analysis
Design for CAP/CLIA, cGMP, IVD
Production Scale-Up
Capacity Planning
Scale-Up Plan
Information Systems
Samples Storage and Disposal
Risks Mitigation
Program Management
Portfolio Prioritization
Strategic Technology Planning
Manufacturing Outsourcing
Prior Work
1
Process Automation
End-to-End NGS Robotic Work-Cells
Integrated Liquid Handler Systems
FFPE Slides Scraping
FFPE Slides Deparaffinization
Large Plasma Volume cfDNA Extraction
Micro-Fluidic Cartridges
Micro-fluidic PCR System
Reagents & Master-mix Systems
Reagents Dispensing
Custom Tools for Ergonomics
LASER Scribing System
Various Custom Lab-Ware
2
Process Optimization
NGS Assay for Microbial Surveillance
NGS Assay for Organs Transplantation
Meta-Genomic Assay for Soil Samples
Droplet Digital PCR Disease Detection
Whole-Exome Sequencing for Oncology
Whole Human Genome Sequencing
Real Time PCR Quantitation
NGS Assays for cfDNA/cfRNA Samples
Six Sigma Quality Control
Samples Storage and Disposal
Automation Software Platforms
Laboratory Information Systems
3
Process Scale Up
Entire Product Automation Plans
Scalable Capacity Planning
Constraints Management
Integrated Automation Software
HT Robotic Systems
HT Reagents Supply & Tracking
Six Sigma Process Optimization
Lean Manufacturing Improvements
Workflows Streamlining
High Capacity Samples Storage
Samples Disposal Plans & Solutions
Multi-Year Strategy Plans
Notable Examples:
Scaling cell-free NGS diagnostic Tests from 100's of samples/day Manual Process to 1000's of samples/day. Fully Automated Workflows, along with Assay Optimization and Cost Savings.
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Design and Development of a custom High-Throughput System for cfDNA Extraction from Large Blood Plasma Volumes along with custom Heater-Shaker, Large Volume Pipetting and Labware.
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End-to-End Automation of Whole Genome NGS Products, enhanced with qPCR Quantitation to Sequence Large Pools of Samples at High-Depth and with Unprecedented Uniformity.
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Development of High-Throughput Robotic Work-cells that can support Multiple NGS Protocols (Hybrid Capture, WGS, cfDNA/RNA...) from Various Sources such as FFPE, Blood, Microbial and Viral samples.
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Design and Development of High-Throughput Automation Systems for Blood, Saliva, Urine, FFPE Tissue, Bacterial Isolates or Soil Samples.